SCHEMBL20809145

SCHEMBL20809145

Cc1ccc2c(c1)-c1nccc3cc(C4CCCC4)cc(c13)C2(C)C

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PDK2 Q15119 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809305 0.86 PDK2 (0.38) PDK2PSMB5
SCHEMBL20809349 0.81 NPC1 (0.32) NPC1RAB9A
SCHEMBL24378892 0.80 PSMB5 (0.34) KDM4EALDH1A1L3MBTL1PSMB5
SCHEMBL20809432 0.77 HTR2A (0.36)
SCHEMBL18365349 0.76 MAOA (0.39) NPC1RAB9AKDM4EALDH1A1L3MBTL1
SCHEMBL25141541 0.75 PSMB5 (0.34) KDM4EALDH1A1L3MBTL1PSMB5
SCHEMBL20809304 0.74 HTR2A (0.32) PDK2
SCHEMBL20809311 0.74 HTR2A (0.36) KDM4E
SCHEMBL20809142 0.71 PDK2 (0.32) PDK2
SCHEMBL26346680 0.70 PSMB5 (0.32) PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 NPC1 3375/4885RAB9A 4437/4885KDM4E 4362/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 NPC1 3375/4885RAB9A 4437/4885KDM4E 4362/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 NPC1 2038/4885RAB9A 3706/4885KDM4E 3879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.