SCHEMBL20809147

SCHEMBL20809147

Cc1cc(-c2ncnc3cc(C4CCCC4)ccc23)cc(C)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMKK1 Q8N5S9 5/20 0.41
CAMKK2 Q96RR4 5/20 0.41
DHODH Q02127 1/20 0.37
SCN9A Q15858 2/20 0.36
KIT P10721 2/20 0.35
AURKA O14965 1/20 0.34
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34
PRKD3 O94806 1/20 0.34
MAP4K4 O95819 1/20 0.34
PAK4 O96013 1/20 0.34
NTRK1 P04629 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
IGF1R P08069 1/20 0.34
MET P08581 1/20 0.34
PIM1 P11309 1/20 0.34
FGFR1 P11362 1/20 0.34
PRKACA P17612 1/20 0.34
FLT1 P17948 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809357 0.87 CAMKK1 (0.42) CAMKK1CAMKK2DHODHKCNH2HRH4
SCHEMBL19258269 0.80 S1PR1 (0.42) CAMKK1CAMKK2DHODHCLK4KCNH2
SCHEMBL26060550 0.79 PRKDC (0.38) CAMKK1CAMKK2SCN9AKITAURKA
SCHEMBL19258069 0.78 CAMKK1 (0.35) CAMKK1CAMKK2DHODHSCN9ACSF1R
SCHEMBL30051741 0.75 MAP4K4 (0.45) SCN9AKITAURKADAPK3JAK2
SCHEMBL17666812 0.75 MAP4K4 (0.45) SCN9AKITAURKADAPK3JAK2
SCHEMBL20809348 0.73 KIT (0.38) CAMKK1CAMKK2SCN9AKITAURKA
SCHEMBL17680548 0.72 SCN9A (0.42) SCN9AKITAURKADAPK3JAK2
SCHEMBL24795204 0.72 CAMKK1 (0.52) CAMKK1CAMKK2DHODHHRH3
SCHEMBL17680367 0.71 KIT (0.36) CAMKK1CAMKK2SCN9AKITAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 CAMKK1 1632/4885CAMKK2 1382/4885DHODH 3548/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 CAMKK1 1632/4885CAMKK2 1382/4885DHODH 3548/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 CAMKK1 3553/4885CAMKK2 3452/4885DHODH 2970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.