SCHEMBL20809348

SCHEMBL20809348

Cc1cc(-c2ncnc3cc(C(C)C)ccc23)cc(C)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIT P10721 3/20 0.38
CAMKK1 Q8N5S9 2/20 0.38
CAMKK2 Q96RR4 2/20 0.38
AURKA O14965 2/20 0.37
DAPK3 O43293 2/20 0.37
JAK2 O60674 2/20 0.37
MAP4K4 O95819 2/20 0.37
PAK4 O96013 2/20 0.37
CSF1R P07333 2/20 0.37
RET P07949 2/20 0.37
IGF1R P08069 2/20 0.37
FLT1 P17948 2/20 0.37
LTK P29376 2/20 0.37
KDR P35968 2/20 0.37
FLT3 P36888 2/20 0.37
MAPK8 P45983 2/20 0.37
CLK2 P49760 2/20 0.37
GSK3A P49840 2/20 0.37
GSK3B P49841 2/20 0.37
CDK7 P50613 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809352 0.85 CAMKK1 (0.39) KITCAMKK1CAMKK2AURKADAPK3
SCHEMBL19258221 0.84 PRKDC (0.38) AURKADAPK3JAK2MAP4K4PAK4
SCHEMBL20809354 0.80 CAMKK1 (0.36) KITCAMKK1CAMKK2AURKADAPK3
SCHEMBL19258245 0.80 SIGMAR1 (0.41) KITLMNAPRKDCKCNH2SCN9A
SCHEMBL30051741 0.79 MAP4K4 (0.45) KITAURKADAPK3JAK2MAP4K4
SCHEMBL17666812 0.79 MAP4K4 (0.45) KITAURKADAPK3JAK2MAP4K4
SCHEMBL24795347 0.78 RXRA (0.35) KITCAMKK1CAMKK2ADORA2APRKDC
SCHEMBL19258252 0.77 LMNA (0.41) CLK4ADORA2ALMNAPRKDCEGFR
SCHEMBL31557866 0.76 PLG (0.36) AURKADAPK3JAK2MAP4K4PAK4
SCHEMBL16339211 0.76 PLG (0.36) AURKADAPK3JAK2MAP4K4PAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 KIT 3050/4885CAMKK1 1632/4885CAMKK2 1382/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 KIT 3050/4885CAMKK1 1632/4885CAMKK2 1382/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 KIT 2906/4885CAMKK1 3553/4885CAMKK2 3452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.