SCHEMBL20809308

SCHEMBL20809308

Cc1cc(C)cc(-c2cc(CC(C)(C)C(F)(F)F)c3c(F)cccc3n2)c1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.35
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
DHODH Q02127 1/20 0.31
HSP90AB1 P08238 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
LMNA P02545 1/20 0.30
PBRM1 Q86U86 1/20 0.30
SDHB P21912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20809043 0.91 PARP1 (0.31) PARP1TNKSTNKS2POLBKMT2A
SCHEMBL20809039 0.82 LMNA (0.43) DHODHMEN1HPGDKMT2ALMNA
SCHEMBL20809038 0.79 LMNA (0.37) DHODHKMT2ALMNA
SCHEMBL20809042 0.78 DHODH (0.37) DHODHMEN1POLBHPGDHTT
SCHEMBL20809037 0.77 NPC1 (0.45) MEN1HTTKMT2ANPSR1LMNA
SCHEMBL20809048 0.77 DHODH (0.43) PARP1TNKSTNKS2DHODHMEN1
SCHEMBL18691144 0.72 IRAK4 (0.31) DHODHSDHB
SCHEMBL20809420 0.72 LMNA (0.48) DHODHHPGDLMNA
SCHEMBL20809067 0.72 ELANE (0.37) PARP1DHODH
SCHEMBL18717002 0.72 ELANE (0.36) PARP1SDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-03-23 US disclosed
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-04 US disclosed
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190103574-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS ACAT1, ACACA, ACAT2 PARP1 1428/4885TNKS 3235/4885TNKS2 3702/4885
US-10957869-B2 Organic luminescent materials containing cycloalkyl ancillary ligands ACAT1, ACACA, ACAT2 PARP1 1428/4885TNKS 3235/4885TNKS2 3702/4885
US-20190077818-A1 ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS FOXO1, NAA15, FOXK1 PARP1 1697/4885TNKS 3851/4885TNKS2 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.