Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.53 |
| ▸ | CTSB | P07858 | 5/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828009 | 1.00 | CTSK (0.53) | CTSKCTSBCAPN1CAPN2SIRT2 | |
| SCHEMBL20828052 | 1.00 | CTSK (0.53) | CTSKCTSBCAPN1CAPN2SIRT2 | |
| SCHEMBL20827895 | 0.94 | CTSK (0.52) | CTSKCTSBCAPN1CAPN2SIRT2 | |
| SCHEMBL20827913 | 0.90 | CAPN1 (0.55) | CTSKCTSBCAPN1CTSL | |
| SCHEMBL20828024 | 0.90 | CAPN1 (0.55) | CTSKCTSBCAPN1CTSL | |
| SCHEMBL20827875 | 0.90 | CAPN1 (0.55) | CTSKCTSBCAPN1CTSL | |
| SCHEMBL20828002 | 0.90 | CAPN1 (0.49) | CTSKCTSBCAPN1CAPN2CTSS | |
| SCHEMBL20828083 | 0.90 | CAPN1 (0.49) | CTSKCTSBCAPN1CAPN2CTSS | |
| SCHEMBL20828001 | 0.86 | CAPN1 (0.51) | CTSKCTSBCAPN1CAPN2CTSS | |
| SCHEMBL20816773 | 0.83 | NPY4R (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190085024-A1 | Alpha-Ketoamide Inhibitors Of Cysteine Proteases | Phelix Therapeutics (US) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190085024-A1 | Alpha-Ketoamide Inhibitors Of Cysteine Proteases | CTSS, CTSB, CTSL | CTSK 9/4885CTSB 2/4885CAPN1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.