SCHEMBL2082995

SCHEMBL2082995

CONC(=O)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
GAA P10253 4/20 0.53
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HTT P42858 2/20 0.53
SLC1A3 P43003 1/20 0.50
KDM4E B2RXH2 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
THRB P10828 1/20 0.49
GFER P55789 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.47
RAB9A P51151 5/20 0.47
RAD51 Q06609 1/20 0.47
HPGD P15428 2/20 0.46
GLA P06280 1/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28963092 0.83 SMN1; SMN2 (0.58) ALDH1A1GAASMN1; SMN2HTTLMNA
SCHEMBL18520106 0.82 TDP1 (0.54) ALDH1A1GAAMAPTSMN1; SMN2HTT
SCHEMBL28962595 0.82 LMNA (0.55) ALDH1A1GAAMAPTSMN1; SMN2HTT
SCHEMBL7712988 0.81 SLC1A3 (0.51) ALDH1A1GAAMAPTSMN1; SMN2HTT
SCHEMBL28962614 0.80 LIPE (0.51) ALDH1A1GAASMN1; SMN2HTTMEN1
SCHEMBL28965293 0.80 MGLL (0.51) ALDH1A1GAAMAPTSMN1; SMN2HTT
SCHEMBL11530552 0.80 ALDH1A1 (0.54) ALDH1A1GAAMAPTSMN1; SMN2HTT
SCHEMBL28962581 0.80 ALDH1A1 (0.53) ALDH1A1GAAMAPTSMN1; SMN2HTT
SCHEMBL15235846 0.79 RAB9A (0.49) ALDH1A1GAAMAPTSMN1; SMN2HTT
SCHEMBL28963089 0.79 ALDH1A1 (0.49) ALDH1A1GAAMAPTSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333633-B Intermediate compound of Rayleigh Lu Geli and preparation method and application thereof 江西科睿药业有限公司 2023-10-20 CN claimed
CN-111423452-B Intermediate of Rayleigh Lu Geli and preparation method and application thereof 江西青峰药业有限公司 2023-08-22 CN claimed
CN-113563304-B Rugol intermediate and preparation method thereof 上海博志研新药物技术有限公司 2022-06-28 CN claimed
CN-113563363-B Ruugeli intermediate, preparation method thereof and preparation method of Ruugeli 上海博志研新药物技术有限公司 2022-06-28 CN claimed
CN-113429423-B Rugoside intermediate and preparation method thereof 上海博志研新药物技术有限公司 2022-05-17 CN claimed
CN-113563303-B Rugoside intermediate and preparation method thereof 上海博志研新药物技术有限公司 2022-04-12 CN claimed
CN-113563363-A Rugoside intermediate, preparation method thereof and preparation method of Rugoside 上海博志研新药物技术有限公司 2021-10-29 CN claimed
CN-113563304-A Rugoside intermediate and preparation method thereof 上海博志研新药物技术有限公司 2021-10-29 CN claimed
CN-113563303-A Rugoside intermediate and preparation method thereof 上海博志研新药物技术有限公司 2021-10-29 CN claimed
CN-113429423-A Rugoside intermediate and preparation method thereof 上海博志研新药物技术有限公司 2021-09-24 CN claimed
CN-111423452-A Rugoside intermediate, preparation method and application thereof 江西青峰药业有限公司 2020-07-17 CN claimed
EP-0327489-B1 Process for the preparation of 14-beta-hydroxy steroids SCHERING AG (DE) 1995-02-15 EP claimed
EP-4619399-A1 NEW SUBSTITUTED TETRAHYDROBENZOXAZEPINE BASF SE (DE) 2025-09-24 EP disclosed
EP-4004001-B1 SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2025-09-03 EP disclosed
CN-116438181-B Sulfonamide substituted heteroaryl pyrimidinediones and uses thereof 广东东阳光药业股份有限公司 2025-01-17 CN disclosed
CN-117843628-A Intermediate of Rayleigh Lu Geli and Rayleigh Lu Geli and preparation method thereof 浙江东亚药业股份有限公司 2024-04-09 CN disclosed
EP-1613613-A2 CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS ANORMED INC. (CA) 2006-01-11 EP disclosed
WO-2004091518-A2 CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS ANORMED INC. (CA) 2004-10-28 WO disclosed
EP-0719780-A1 Organic Phosphoric acid ester derivatives NIHON BAYER AGROCHEM K.K. (JP) 1996-07-03 EP disclosed
US-4234572-A AMINOGLYCOSIDE ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US disclosed