Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20830750 | 0.86 | ITGB1 (0.42) | ALDH1A1ITGB1ITGA4USP2L3MBTL1 | |
| SCHEMBL13668090 | 0.86 | ITGB1 (0.42) | ALDH1A1ITGB1ITGA4USP2L3MBTL1 | |
| SCHEMBL20830620 | 0.83 | ITGB1 (0.40) | TSHRALDH1A1ITGB1ITGA4HDAC2 | |
| SCHEMBL20830444 | 0.78 | ITGB1 (0.38) | HSD17B10ALDH1A1ITGB1ITGA4L3MBTL1 | |
| SCHEMBL19869069 | 0.77 | CYP1A2 (0.49) | ALDH1A1MAPTHTTITGB1ITGA4 | |
| SCHEMBL22307325 | 0.77 | TSHR (0.40) | TSHRHSD17B10LMNAKMT2AALDH1A1 | |
| SCHEMBL20980012 | 0.77 | TSHR (0.40) | TSHRHSD17B10LMNAKMT2AALDH1A1 | |
| SCHEMBL20850510 | 0.77 | KIF11 (0.39) | HSD17B10ALDH1A1ITGB1ITGA4USP2 | |
| SCHEMBL284589 | 0.76 | TSHR (0.63) | TSHRHSD17B10LMNAKMT2AALDH1A1 | |
| SCHEMBL13243712 | 0.75 | TSHR (0.46) | TSHRHSD17B10LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548851-B2 | Method for preparation of n-acetyl cysteine amide and derivatives thereof | NACUITY PHARMACEUTICALS, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20220024866-A1 | Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof | NACUITY PHARMACEUTICALS, INC. | 2022-01-27 | — | — | US | disclosed |
| US-11091433-B2 | Method for preparation of N-acetyl cysteine amide and derivatives thereof | Nacuity Pharmaceutials, Inc. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20200277258-A1 | Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof | NACUITY PHARMACEUTICALS, INC. | 2020-09-03 | — | — | US | disclosed |
| US-10590073-B2 | Method for preparation of N-acetyl cysteine amide and derivatives thereof | NACUITY PHARMACEUTICALS, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| WO-2019060623-A1 | METHOD FOR PREPARATION OF N-ACETYL CYSTEINE AMIDE AND DERIVATIVES THEREOF | NACUITY PHARMACEUTICALS, INC. (US) | 2019-03-28 | — | — | WO | disclosed |
| US-20190084926-A1 | Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof | NACUITY PHARMACEUTICALS, INC. | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548851-B2 | Method for preparation of n-acetyl cysteine amide and derivatives thereof | AADAC, GCLC, DDC | TSHR 2622/4885HSD17B10 2027/4885LMNA 1577/4885 |
| US-20220024866-A1 | Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof | AADAC, GCLC, DDC | TSHR 2622/4885HSD17B10 2027/4885LMNA 1577/4885 |
| US-20200277258-A1 | Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof | AADAC, GCLC, DDC | TSHR 2622/4885HSD17B10 2027/4885LMNA 1577/4885 |
| US-10590073-B2 | Method for preparation of N-acetyl cysteine amide and derivatives thereof | CTH, AHCY, AADAT | TSHR 2251/4885HSD17B10 1199/4885LMNA 3350/4885 |
| US-20190084926-A1 | Method for Preparation of N-Acetyl Cysteine Amide and Derivatives Thereof | CTH, AHCY, AADAT | TSHR 2251/4885HSD17B10 1199/4885LMNA 3350/4885 |
| US-11091433-B2 | Method for preparation of N-acetyl cysteine amide and derivatives thereof | AADAC, GCLC, DDC | TSHR 2622/4885HSD17B10 2027/4885LMNA 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.