Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18268335 | 1.00 | CTSS (0.49) | CTSSCTSKCHRM3CHRM2CHRM1 | |
| SCHEMBL18261794 | 0.86 | CTSK (0.50) | CTSSCTSKCHRM3SCN9A | |
| SCHEMBL18268319 | 0.86 | CTSK (0.52) | CTSSCTSKCHRM3MAPTSCN9A | |
| SCHEMBL18268310 | 0.85 | CHRM3 (0.50) | CTSSCTSKCHRM3 | |
| SCHEMBL18260361 | 0.85 | CHRM3 (0.50) | CTSSCTSKCHRM3 | |
| SCHEMBL8512028 | 0.85 | LMNA (0.60) | CTSSCTSKCHRM3CHRM2CHRM1 | |
| SCHEMBL8512022 | 0.85 | LMNA (0.60) | CTSSCTSKCHRM3CHRM2CHRM1 | |
| SCHEMBL8512023 | 0.85 | LMNA (0.60) | CTSSCTSKCHRM3CHRM2CHRM1 | |
| SCHEMBL18268321 | 0.83 | CHRNB2 (0.49) | CTSSCTSKCHRM3CYP2D6 | |
| SCHEMBL18260391 | 0.83 | CHRNB2 (0.49) | CTSSCTSKCHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303328-B1 | AMINOESTER DERIVATIVES | CHIESI FARM SPA (IT) | 2019-03-20 | — | — | EP | disclosed |