Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 14/20 | 0.69 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831386 | 0.84 | TRPC5 (0.76) | TRPC5KMT2AMEN1 | |
| SCHEMBL20818186 | 0.83 | TRPC5 (0.71) | TRPC5TNKSPARP1TNKS2 | |
| SCHEMBL20818113 | 0.81 | TRPC5 (1.00) | TRPC5TNKSPARP1TNKS2KMT2A | |
| SCHEMBL25697325 | 0.79 | TRPC5 (0.49) | TRPC5TNKSPARP1TNKS2 | |
| SCHEMBL30476388 | 0.78 | TRPC5 (1.00) | TRPC5TNKSPARP1TNKS2LMNA | |
| SCHEMBL20818084 | 0.78 | TRPC5 (1.00) | TRPC5TNKSPARP1TNKS2LMNA | |
| SCHEMBL20817933 | 0.77 | TRPC5 (0.65) | TRPC5TNKSPARP1TNKS2KMT2A | |
| SCHEMBL20817958 | 0.77 | TRPC5 (0.71) | TRPC5TNKSPARP1TNKS2KMT2A | |
| SCHEMBL20832016 | 0.76 | TRPC5 (0.58) | TRPC5TNKSPARP1TNKS2KMT2A | |
| SCHEMBL25688270 | 0.75 | TRPC5 (0.57) | TRPC5TNKSPARP1TNKS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | PDXK, ATP6V1B1, REN | TRPC5 1439/4885TNKS 1544/4885PARP1 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.