Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493596 | 0.81 | PTPN2 (0.44) | ALDH1A1KMT2ANPSR1CYP2A6KDM4E | |
| SCHEMBL15651775 | 0.79 | BCAT2 (0.47) | ALDH1A1KMT2AMAPK8MAPK10CYP2A6 | |
| SCHEMBL5187882 | 0.79 | KMT2A (0.51) | ALDH1A1KMT2ANPSR1MAPK10POLB | |
| SCHEMBL2187456 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HTTKMT2APPARGNCOR2 | |
| SCHEMBL2652907 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2ANPSR1RXFP1MAPK8 | |
| SCHEMBL4418474 | 0.73 | CYP2A6 (0.36) | KMT2ACYP2A6TRIM24TRIM33ERN1 | |
| SCHEMBL3783766 | 0.72 | PRNP (0.39) | ALDH1A1HTTKMT2APRNPPPARG | |
| SCHEMBL2928256 | 0.71 | — | — | |
| SCHEMBL4556834 | 0.71 | PRNP (0.45) | ALDH1A1HTTKMT2APRNPPPARG | |
| SCHEMBL10442 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3023420-A1 | Methods for providing stable isoindole derivatives | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-05-25 | — | — | EP | claimed |
| US-20160137601-A1 | METHOD FOR PROVIDING STABLE ISOINDOLE DERIVATIVES | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V (DE) | 2016-05-19 | — | — | US | claimed |
| EP-3023420-A1 | Methods for providing stable isoindole derivatives | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-05-25 | — | — | EP | disclosed |
| US-20160137601-A1 | METHOD FOR PROVIDING STABLE ISOINDOLE DERIVATIVES | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V (DE) | 2016-05-19 | — | — | US | disclosed |
| US-20130023171-A1 | Composition and Method For Improving Adhesion of Textile Substrates to Rubber and Articles Resulting Therefrom | BROWN HAROLD M (US) | 2013-01-24 | — | — | US | disclosed |
| EP-1854791-B1 | NOVEL THIOPHENE COMPOUND AND PROCESS FOR PRODUCING CAFFENOFURAN OR ANALOGUE THEREOF FROM THE SAME | SAN EI GEN FFI INC (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-7897790-B2 | synthetic intermediate that is useful for efficient production of kahweofuran; flavoring; when thiophene compound is reacted in hydrogen atmosphere using transition metal catalyst, cyclization occurs simultaneously with reduction, to produce a 2,3-dihydrothieno[2,3c]furan skeleton in a single step | SAN-EI GEN F.F.I., INC. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-7897790-B2 | synthetic intermediate that is useful for efficient production of kahweofuran; flavoring; when thiophene compound is reacted in hydrogen atmosphere using transition metal catalyst, cyclization occurs simultaneously with reduction, to produce a 2,3-dihydrothieno[2,3c]furan skeleton in a single step | SAN-EI GEN F.F.I., INC. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-7897790-B2 | synthetic intermediate that is useful for efficient production of kahweofuran; flavoring; when thiophene compound is reacted in hydrogen atmosphere using transition metal catalyst, cyclization occurs simultaneously with reduction, to produce a 2,3-dihydrothieno[2,3c]furan skeleton in a single step | SAN-EI GEN F.F.I., INC. (JP) | 2011-03-01 | — | — | US | disclosed |
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | SAN EI GEN F.F.I., INC. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | SAN EI GEN F.F.I., INC. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | SAN EI GEN F.F.I., INC. (JP) | 2008-07-10 | — | — | US | disclosed |
| EP-1854791-A1 | NOVEL THIOPHENE COMPOUND AND PROCESS FOR PRODUCING CAFFENOFURAN OR ANALOGUE THEREOF FROM THE SAME | SAN-EI GEN F.F.I., INC. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137601-A1 | METHOD FOR PROVIDING STABLE ISOINDOLE DERIVATIVES | DYNC1I2, FKBP8, FKBP5 | ALDH1A1 2155/4885HTT 59/4885KMT2A 2731/4885 |
| US-20080167481-A1 | Novel Thiophene Compound and Process for Producing Caffenofuran or Analogue Thereof from the Same | CYP4F3, CBR3, GTF3C4 | ALDH1A1 295/4885HTT 2408/4885KMT2A 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.