Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874678 | 0.78 | HSD11B1 (0.65) | HSD11B1P2RX7CYP19A1SIRT2SIRT1 | |
| SCHEMBL15875458 | 0.78 | HSD11B1 (0.61) | HSD11B1P2RX7SIRT2SIRT1GAA | |
| SCHEMBL4195851 | 0.76 | HSD11B1 (0.61) | HSD11B1P2RX7CYP19A1SIRT2SIRT1 | |
| SCHEMBL2898638 | 0.76 | HSD11B1 (0.58) | HSD11B1P2RX7CYP19A1SIRT2SIRT1 | |
| SCHEMBL21606708 | 0.75 | HSD11B1 (0.77) | HSD11B1P2RX7SIRT2SIRT1GAA | |
| SCHEMBL18359857 | 0.74 | HSD11B1 (0.56) | HSD11B1P2RX7CYP19A1SIRT2SIRT1 | |
| SCHEMBL27855037 | 0.74 | HSD11B1 (0.56) | HSD11B1P2RX7CYP19A1SIRT2SIRT1 | |
| SCHEMBL11913659 | 0.73 | HSD11B1 (0.55) | HSD11B1P2RX7CYP19A1SIRT2SIRT1 | |
| SCHEMBL23812236 | 0.72 | HSD11B1 (0.59) | HSD11B1SIRT2SIRT1DUT | |
| SCHEMBL15875668 | 0.72 | HSD11B1 (0.53) | HSD11B1P2RX7SIRT2SIRT1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200197526-A1 | REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-06-25 | — | — | US | disclosed |
| US-10240195-B2 | Chemical methods for producing tagged nucleotides | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200197526-A1 | REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF | LDLR, LIPA, ABCB11 | HSD11B1 2280/4885P2RX7 3159/4885NPC1 8/4885 |
| US-10240195-B2 | Chemical methods for producing tagged nucleotides | NT5C3B, NCL, NUDT1 | HSD11B1 4373/4885P2RX7 1289/4885NPC1 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.