Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29554163 | 0.85 | ALDH1A1 (0.39) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL93457 | 0.85 | ALDH1A1 (0.39) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL346904 | 0.85 | TRIM24 (0.59) | TRIM24TRIM33KMT2AMEN1LMNA | |
| Imidazole SCHEMBL11142652 | 0.84 | ALDH1A1 (0.38) | TRIM24TRIM33KMT2AALDH1A1 | |
| SCHEMBL4322480 | 0.83 | TRIM24 (0.53) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL30556656 | 0.83 | TRIM24 (0.53) | TRIM24TRIM33KMT2AMEN1LMNA | |
| Ammonia Solution, Strong SCHEMBL28157558 | 0.83 | ALDH1A1 (0.38) | TRIM24TRIM33KMT2AMEN1LMNA | |
| Benzene SCHEMBL28129976 | 0.83 | ALDH1A1 (0.38) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL11090010 | 0.81 | ALDH1A1 (0.41) | TRIM24TRIM33KMT2AMEN1LMNA | |
| SCHEMBL24466129 | 0.79 | ALDH1A1 (0.35) | TRIM24TRIM33KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12582645-B2 | Chemokine CXCR4 receptor modulators and uses related thereto | EMORY UNIVERSITY (US) | 2026-03-24 | — | — | US | disclosed |
| US-20240316034-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2024-09-26 | — | — | US | disclosed |
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | GFB (ABC), LLC | 2023-06-29 | — | — | US | disclosed |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-11497744-B2 | Chemokine CXCR4 receptor modulators and uses related thereto | EMORY UNIVERSITY (US) | 2022-11-15 | — | — | US | disclosed |
| EP-1613613-B1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
| CN-110545814-A | Chemokine CXCR4 receptor modulators and uses related thereto | UNIV EMORY | 2019-12-06 | — | — | CN | disclosed |
| WO-2018156595-A1 | CHEMOKINE CXCR4 RECEPTOR MODULATORS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2018-08-30 | — | — | WO | disclosed |
| CN-103570683-B | Polysubstituted aminated compounds and its preparation method and application | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |
| CN-102675305-B | Imidazopyridine compounds, as well as preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2014-11-12 | — | — | CN | disclosed |
| CN-103570683-A | Multi-substituted amine compound, as well as preparation method and use thereof | SHANGHAI INST MATERIA MEDICA | 2014-02-12 | — | — | CN | disclosed |
| CN-103086958-A | NF[kappa]B pathway activation inhibitor, preparation method thereof, pharmaceutical composition and purpose | SHANGHAI INST MATERIA MEDICA | 2013-05-08 | — | — | CN | disclosed |
| CN-102675305-A | Imidazopyridine compounds, as well as preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-09-19 | — | — | CN | disclosed |
| US-7863293-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2011-01-04 | — | — | US | disclosed |
| WO-2010120621-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-21 | — | — | WO | disclosed |
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED CORPORATION (CA) | 2008-10-16 | — | — | US | disclosed |
| US-7291631-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2007-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203028-A1 | PYRIDAZINONES AND METHODS OF USE THEREOF | PDXK, ATP6V1B1, REN | TRIM24 4864/4885TRIM33 4759/4885KMT2A 3397/4885 |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | TRIM24 2344/4885TRIM33 2492/4885KMT2A 4253/4885 |
| US-20240316034-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | TRIM24 2344/4885TRIM33 2492/4885KMT2A 4253/4885 |
| US-11497744-B2 | Chemokine CXCR4 receptor modulators and uses related thereto | CXCR4, CXCL12, CXCR1 | TRIM24 2344/4885TRIM33 2492/4885KMT2A 4253/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | TRIM24 2344/4885TRIM33 2492/4885KMT2A 4253/4885 |
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | CXCR4, CXCR1, CXCR3 | TRIM24 2478/4885TRIM33 2741/4885KMT2A 2950/4885 |
| US-12582645-B2 | Chemokine CXCR4 receptor modulators and uses related thereto | CXCR4, CXCR2, CXCR1 | TRIM24 2319/4885TRIM33 2509/4885KMT2A 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.