SCHEMBL20847503

SCHEMBL20847503

CC(C)N(Cc1c(F)cc(F)cc1F)Sc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20847641 0.80 SLC6A2 (0.40) RIPK1
SCHEMBL20847654 0.73 ALDH1A1 (0.38) RIPK1
SCHEMBL20847500 0.70 RIPK1 (0.31) RIPK1
SCHEMBL20847502 0.69 RIPK1 (0.35) RIPK1
SCHEMBL20847508 0.67 HDAC6 (0.48) RIPK1
SCHEMBL12304304 0.60 HPGD (0.34) RIPK1
SCHEMBL20847571 0.59 PYCR1 (0.43) RIPK1
SCHEMBL25946401 0.57 DPP4 (0.39)
SCHEMBL25650296 0.57 GCGR (0.37) RIPK1
SCHEMBL3021249 0.57 RIPK1 (0.32) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019056120-A1 PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF DALRIADA THERAPEUTICS INC. (CA) 2019-03-28 WO disclosed