Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 6/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847654 | 0.82 | ALDH1A1 (0.38) | SLC6A2SLC6A3RIPK1KDM4EALDH1A1 | |
| SCHEMBL20847503 | 0.80 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL20847791 | 0.72 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3RIPK1IDO1 | |
| SCHEMBL20847474 | 0.72 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3RIPK1IDO1 | |
| SCHEMBL20847640 | 0.70 | HDAC6 (0.48) | SLC6A2SLC6A4SLC6A3RIPK1SMN1; SMN2 | |
| SCHEMBL6856773 | 0.68 | RIPK1 (0.53) | SLC6A2SLC6A4SLC6A3RIPK1IDO1 | |
| SCHEMBL19143940 | 0.68 | RIPK1 (0.43) | SLC6A2SLC6A4SLC6A3RIPK1IDO1 | |
| SCHEMBL22909581 | 0.67 | DAO (0.37) | SLC6A2SLC6A4SLC6A3RIPK1IDO1 | |
| SCHEMBL10586299 | 0.66 | TYR (0.56) | SLC6A2SLC6A4SLC6A3RIPK1IDO1 | |
| SCHEMBL434483 | 0.65 | IDO1 (0.46) | SLC6A2SLC6A4SLC6A3IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |