Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847506 | 0.95 | EPHX1 (0.43) | HDAC8HDAC6CYP4A11HDAC3HDAC11 | |
| SCHEMBL20847775 | 0.85 | KMT2A (0.44) | HDAC8HDAC6HDAC3HDAC11MEN1 | |
| SCHEMBL24473070 | 0.84 | HDAC6 (0.61) | HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847480 | 0.84 | HDAC6 (0.43) | HDAC8HDAC6HDAC3HDAC11 | |
| SCHEMBL20847785 | 0.83 | LMNA (0.47) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL20847622 | 0.81 | L3MBTL1 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL20847664 | 0.79 | ESR1 (0.38) | HDAC8HDAC6HDAC3HDAC11ALDH1A1 | |
| SCHEMBL20847642 | 0.77 | SLC6A4 (0.35) | HDAC8HDAC6KDM4EMEN1KMT2A | |
| SCHEMBL20847604 | 0.76 | SLC6A2 (0.38) | HDAC8HDAC6HDAC3HDAC11PSEN1 | |
| SCHEMBL24473204 | 0.75 | HDAC6 (0.62) | HDAC8HDAC6HDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |