Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847480 | 0.88 | HDAC6 (0.43) | HDAC8HDAC6HDAC11HDAC3NSD2 | |
| SCHEMBL24473070 | 0.86 | HDAC6 (0.61) | HDAC8HDAC6HDAC11HDAC3 | |
| SCHEMBL20847600 | 0.85 | HDAC8 (0.43) | KMT2AMEN1HDAC8HDAC6HDAC11 | |
| SCHEMBL20847664 | 0.83 | ESR1 (0.38) | HDAC8HDAC6HDAC11HDAC3NSD2 | |
| SCHEMBL20847785 | 0.82 | LMNA (0.47) | KMT2AMEN1ALDH1A1AGERMTNR1A | |
| SCHEMBL20847506 | 0.80 | EPHX1 (0.43) | KMT2AMEN1HDAC8HDAC6HDAC11 | |
| SCHEMBL20847604 | 0.80 | SLC6A2 (0.38) | HDAC8HDAC6HDAC11HDAC3AGER | |
| SCHEMBL20847477 | 0.79 | SLC6A2 (0.39) | HDAC8HDAC6HDAC11HDAC3ALDH1A1 | |
| SCHEMBL20847602 | 0.79 | AGER (0.38) | KMT2AMEN1HDAC8HDAC6HDAC3 | |
| SCHEMBL20847642 | 0.78 | SLC6A4 (0.35) | KMT2AMEN1HDAC8HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |