Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847775 | 0.88 | KMT2A (0.44) | HDAC6HDAC8HDAC3HDAC11NSD2 | |
| SCHEMBL24473070 | 0.85 | HDAC6 (0.61) | HDAC6HDAC8HDAC3HDAC11 | |
| SCHEMBL22482913 | 0.84 | HDAC6 (0.43) | HDAC6HDAC8HDAC3HDAC11NSD2 | |
| SCHEMBL20847600 | 0.84 | HDAC8 (0.43) | HDAC6HDAC8HDAC3HDAC11 | |
| SCHEMBL20847664 | 0.82 | ESR1 (0.38) | HDAC6HDAC8HDAC3HDAC11NSD2 | |
| SCHEMBL20847506 | 0.79 | EPHX1 (0.43) | HDAC6HDAC8HDAC3HDAC11 | |
| SCHEMBL20847604 | 0.79 | SLC6A2 (0.38) | HDAC6HDAC8HDAC3HDAC11 | |
| SCHEMBL20847477 | 0.78 | SLC6A2 (0.39) | HDAC6HDAC8HDAC3HDAC11 | |
| SCHEMBL20847602 | 0.77 | AGER (0.38) | HDAC6HDAC8HDAC3NSD2 | |
| SCHEMBL20847650 | 0.76 | ALDH1A1 (0.35) | HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |