Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847664 | 0.82 | ESR1 (0.38) | ALDH1A1HDAC8HDAC6 | |
| SCHEMBL20847604 | 0.82 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3HDAC8HDAC6 | |
| SCHEMBL20847622 | 0.82 | L3MBTL1 (0.40) | ALDH1A1 | |
| SCHEMBL20847477 | 0.81 | SLC6A2 (0.39) | SLC6A4KDM4EALDH1A1SLC6A2HDAC8 | |
| SCHEMBL20847602 | 0.81 | AGER (0.38) | SLC6A4ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL20847669 | 0.79 | AGER (0.40) | SLC6A4ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL20847650 | 0.79 | ALDH1A1 (0.35) | KDM4EALDH1A1LMNAHDAC8HDAC6 | |
| SCHEMBL20847740 | 0.79 | NSD2 (0.47) | SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL20847575 | 0.78 | AGER (0.42) | SLC6A4ALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL20847775 | 0.78 | KMT2A (0.44) | ALDH1A1HDAC8HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |