Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22909374 | 0.73 | TAAR1 (0.39) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7700904 | 0.72 | IDO1 (0.58) | DAOHTR2AHTR2CIDO1AGXT | |
| SCHEMBL22909268 | 0.71 | ALDH1A1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL22909233 | 0.71 | GFER (0.42) | ALDH1A1MAOB | |
| SCHEMBL22909382 | 0.68 | SIGMAR1 (0.40) | HTR2ASLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL22909452 | 0.68 | CYP2A6 (0.38) | DAOIDO1MAOBKCNH2 | |
| SCHEMBL22909609 | 0.67 | SIGMAR1 (0.31) | — | |
| SCHEMBL20847641 | 0.67 | SLC6A2 (0.40) | HTR2AHTR2CIDO1AGXTRIPK1 | |
| SCHEMBL27465879 | 0.66 | DAO (0.47) | DAOHTR2AHTR2CIDO1AGXT | |
| SCHEMBL1121847 | 0.65 | IDO1 (0.50) | DAOHTR2AHTR2CIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |