Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847791 | 0.97 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL20847761 | 0.82 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL20847500 | 0.81 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL20847502 | 0.79 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL20847720 | 0.79 | ALDH1A1 (0.41) | SLC6A2SLC6A4SLC6A3SMN1; SMN2RORC | |
| SCHEMBL20847602 | 0.78 | AGER (0.38) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL20847666 | 0.77 | SLC6A3 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20847669 | 0.77 | AGER (0.40) | SLC6A2SLC6A4SLC6A3CTSLALDH1A1 | |
| SCHEMBL20847575 | 0.75 | AGER (0.42) | SLC6A2SLC6A4SLC6A3SMN1; SMN2ALDH1A1 | |
| SCHEMBL20847492 | 0.75 | HDAC8 (0.37) | SLC6A2SLC6A4SLC6A3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |