SCHEMBL20848347

SCHEMBL20848347

CC1(C(=O)OCc2ccc(COC(=O)C3(C)COC(=O)OC3)cc2)COC(=O)OC1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
POLB P06746 1/20 0.39
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
CYP17A1 P05093 1/20 0.36
CYP19A1 P11511 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NAAA Q02083 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21011264 0.95 MEN1 (0.42) CYP3A4POLBDDB1CRBNCYP17A1
SCHEMBL18256732 0.94 NAAA (0.41) POLBALDH1A1MEN1KMT2ANAAA
SCHEMBL15198823 0.94 NAAA (0.41) CYP3A4POLBDDB1CRBNCYP17A1
SCHEMBL847109 0.94 POLB (0.35) CYP3A4POLBDDB1CRBNCYP17A1
SCHEMBL12938576 0.93 POLB (0.38) CYP3A4POLBDDB1CRBNCYP17A1
SCHEMBL846827 0.92 ALDH1A1 (0.47) DDB1CRBNALDH1A1KMT2A
SCHEMBL24885613 0.90 NAAA (0.44) POLBALDH1A1MEN1KMT2ANAAA
SCHEMBL663919 0.80 ATM (0.50) CYP3A4POLBALDH1A1MEN1KMT2A
SCHEMBL18257753 0.79 CHRM5 (0.34)
SCHEMBL12938624 0.79 NAAA (0.45) CYP3A4ALDH1A1MEN1KMT2ANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190091338-A1 MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190091338-A1 MIKTO-ARM STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS COQ8A, COQ8B, STARD7 CYP3A4 1255/4885POLB 485/4885DDB1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.