SCHEMBL847109

SCHEMBL847109

CC1(C(=O)OCc2ccc(CO)cc2)COC(=O)OC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.35
CYP3A4 P08684 1/20 0.35
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP17A1 P05093 1/20 0.33
CYP19A1 P11511 1/20 0.33
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848347 0.94 CYP3A4 (0.39) POLBCYP3A4DDB1CRBNALDH1A1
SCHEMBL21011264 0.90 MEN1 (0.42) POLBCYP3A4DDB1CRBNALDH1A1
SCHEMBL18256732 0.89 NAAA (0.41) POLBSMN1; SMN2ALDH1A1CA2CA9
SCHEMBL15198823 0.89 NAAA (0.41) POLBCYP3A4DDB1CRBNALDH1A1
SCHEMBL12938576 0.87 POLB (0.38) POLBCYP3A4DDB1CRBNHPGD
SCHEMBL846827 0.87 ALDH1A1 (0.47) DDB1CRBNALDH1A1CA12CA2
SCHEMBL24885613 0.85 NAAA (0.44) POLBSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL28897145 0.84 POLB (0.36) POLBCYP3A4DDB1CRBNHPGD
SCHEMBL663919 0.75 ATM (0.50) POLBCYP3A4SMN1; SMN2ALDH1A1MEN1
SCHEMBL18257753 0.74 CHRM5 (0.34) SMN1; SMN2CA12CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-11-23 US disclosed
US-11149114-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-10-19 US disclosed
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2021-04-20 US disclosed
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC. (US) 2020-09-22 US disclosed
EP-3259292-B1 BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) 2020-04-08 EP disclosed
US-10457759-B2 Co-delivery of cholesterol lowering drugs and nutraceuticals INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-10-29 US disclosed
US-10259907-B2 Block copolymers with surface-active junction groups, compositions and processes thereof AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.À R.L. (LU) 2019-04-16 US disclosed
US-20190023824-A1 CO-DELIVERY OF CHOLESTEROL LOWERING DRUGS AND NUTRACEUTICALS INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-01-24 US disclosed
WO-2011078804-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-06-30 WO disclosed
WO-2011078805-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-06-30 WO disclosed
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11149114-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto DCLRE1A, ODC1, MRTO4 POLB 688/4885CYP3A4 4096/4885DDB1 804/4885
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto DCLRE1A, ODC1, MRTO4 POLB 688/4885CYP3A4 4096/4885DDB1 804/4885
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS POLB 1100/4885CYP3A4 4085/4885DDB1 1493/4885
US-10457759-B2 Co-delivery of cholesterol lowering drugs and nutraceuticals STARD3, HMGCR, CETP POLB 2139/4885CYP3A4 493/4885DDB1 1150/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS POLB 1100/4885CYP3A4 4085/4885DDB1 1493/4885
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF MLEC, NOD2, PAM POLB 249/4885CYP3A4 4614/4885DDB1 891/4885
US-20190023824-A1 CO-DELIVERY OF CHOLESTEROL LOWERING DRUGS AND NUTRACEUTICALS STARD3, HMGCR, CETP POLB 2139/4885CYP3A4 493/4885DDB1 1150/4885
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA POLB 707/4885CYP3A4 2622/4885DDB1 3354/4885
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS POLB 1100/4885CYP3A4 4085/4885DDB1 1493/4885
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO SAMM50, ADRM1, UFM1 POLB 451/4885CYP3A4 947/4885DDB1 282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.