SCHEMBL20850482

SCHEMBL20850482

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc2c(c1)C1(c3ccccc3-c3ccccc31)c1cc(-n3c4ccc(C(C)(C)C)cc4c4cc(C(C)(C)C)ccc43)ccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PLA2G1B P04054 1/20 0.39
NFKB1 P19838 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
DNMT1 P26358 3/20 0.37
PGR P06401 1/20 0.34
RORA P35398 1/20 0.34
RORC P51449 1/20 0.34
RORB Q92753 1/20 0.34
PDK2 Q15119 12/20 0.34
KIF11 P52732 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21138935 0.95 NPC1 (0.35) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL17827194 0.92 DNMT1 (0.37) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL23050928 0.88 DNMT1 (0.31) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL12292089 0.88 L3MBTL1 (0.39) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL2604393 0.87 NPC1 (0.37) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL2244249 0.86 MEN1 (0.41) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30107697 0.86 MEN1 (0.41) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL23050918 0.86 KIF11 (0.31) DNMT1KIF11
SCHEMBL23050917 0.86 DNMT1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL23050900 0.86 DNMT1 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11121182-B2 Organic photoelectric conversion element, optical area sensor, image pickup device, and image pickup apparatus CANON KABUSHIKI KAISHA (JP) 2021-09-14 US disclosed
EP-3466937-B1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE CANON KK (JP) 2021-03-24 EP disclosed
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device CANON KABUSHIKI KAISHA (JP) 2021-03-16 US disclosed
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-12-22 US disclosed
US-20190115545-A1 ORGANIC COMPOUND, AND PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE USING THE ORGANIC COMPOUND CANON KABUSHIKI KAISHA (JP) 2019-04-18 US disclosed
EP-3466937-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR AND IMAGING DEVICE C/o Canon Kabushiki Kaisha (JP) 2019-04-10 EP disclosed
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE CANON KABUSHIKI KAISHA (JP) 2019-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190092743-A1 PHOTOELECTRIC CONVERSION ELEMENT, TWO-DIMENSIONAL SENSOR, IMAGE SENSOR, AND IMAGE PICKUP DEVICE NR2E3, CRY2, GPR3 NPC1 3567/4885ALDH1A1 602/4885PLA2G1B 3110/4885
US-10873032-B2 Organic photoelectric conversion element, two-dimensional sensor, image sensor, and imaging apparatus POU2F1, PPOX, POU2F2 NPC1 857/4885ALDH1A1 1143/4885PLA2G1B 4756/4885
US-20190115545-A1 ORGANIC COMPOUND, AND PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE USING THE ORGANIC COMPOUND NR2E1, NR2E3, POU2F1 NPC1 1482/4885ALDH1A1 930/4885PLA2G1B 4245/4885
US-10947212-B2 Photoelectric conversion element, two-dimensional sensor, image sensor, and image pickup device NR2E3, CRY2, GPR3 NPC1 3567/4885ALDH1A1 602/4885PLA2G1B 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.