Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26422975 | 0.79 | GPR84 (0.38) | MAPTLOXL2ALDH1A1GPR84EIF4A3 | |
| SCHEMBL764523 | 0.75 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL24414591 | 0.75 | RHEB (0.41) | LOXL2GPR84EIF4A3NPC1RAB9A | |
| SCHEMBL30991851 | 0.75 | RHEB (0.41) | LOXL2GPR84EIF4A3NPC1RAB9A | |
| SCHEMBL26262596 | 0.74 | NR3C1 (0.34) | LOXL2GPR84EIF4A3 | |
| SCHEMBL12056086 | 0.74 | ALDH1A1 (0.38) | MAPTLOXL2ALDH1A1GPR84DRD4 | |
| SCHEMBL12334164 | 0.73 | LOXL2 (0.64) | MAPTLOXL2ALDH1A1GAAHPGD | |
| SCHEMBL14081528 | 0.73 | FLT3 (0.47) | LOXL2GAAALOX15SMN1; SMN2MTNR1A | |
| SCHEMBL2111019 | 0.72 | LOXL2 (0.58) | MAPTLOXL2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14493641 | 0.71 | LOXL2 (0.62) | MAPTLOXL2ALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684767-B1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2024-04-24 | — | — | EP | disclosed |
| WO-2019058393-A1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-03-28 | — | — | WO | disclosed |