Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056086 | 0.83 | ALDH1A1 (0.38) | LOXL2 | |
| SCHEMBL20853019 | 0.75 | MAPT (0.40) | LOXL2 | |
| SCHEMBL13062674 | 0.70 | KEAP1 (0.44) | — | |
| SCHEMBL27308379 | 0.67 | DAO (0.39) | — | |
| SCHEMBL832561 | 0.66 | XDH (0.48) | — | |
| SCHEMBL26422975 | 0.65 | GPR84 (0.38) | LOXL2 | |
| SCHEMBL14845717 | 0.65 | DAO (0.33) | — | |
| SCHEMBL11888191 | 0.65 | — | — | |
| SCHEMBL25156359 | 0.64 | KDM5A (0.49) | — | |
| SCHEMBL25156192 | 0.63 | KDM5A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577301-B1 | Antithrombotic diaminocyclohexane derivatives | DAIICHI SANKYO CO LTD (JP) | 2012-09-12 | — | — | EP | disclosed |
| EP-1405852-B1 | DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2012-08-01 | — | — | EP | disclosed |
| EP-2431370-A1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2012-03-21 | — | — | EP | disclosed |