Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20853323 | 0.81 | CA12 (0.39) | TSHRTP53MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL20853244 | 0.77 | ABCC2 (0.47) | TSHRL3MBTL1KMT2AMEN1ABCC2 | |
| SCHEMBL20853229 | 0.74 | KDM4E (0.40) | TSHRTP53L3MBTL1KMT2AMEN1 | |
| SCHEMBL27366620 | 0.74 | CNR2 (0.45) | TSHRTP53L3MBTL1POLBABCC2 | |
| SCHEMBL20853006 | 0.72 | CCR2 (0.54) | L3MBTL1KMT2AMEN1CCR2KDM4E | |
| SCHEMBL20853230 | 0.71 | PPARG (0.46) | CCR2KDM4ENOD2NOD1ALDH1A1 | |
| SCHEMBL20853220 | 0.70 | CNR2 (0.40) | TSHRKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL20937290 | 0.69 | CCR2 (0.56) | TSHRKMT2AMEN1POLBCCR2 | |
| SCHEMBL7971398 | 0.69 | GRIN2D (0.51) | KMT2AMEN1ABCC2GRIN2DGRIN3B | |
| SCHEMBL20853004 | 0.68 | L3MBTL1 (0.50) | TSHRTP53L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019058393-A1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-03-28 | — | — | WO | disclosed |