Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20853244 | 0.84 | ABCC2 (0.47) | CNR2CNR1ABCC2ALDH1A1L3MBTL1 | |
| SCHEMBL25145277 | 0.84 | CNR2 (0.48) | CNR2CNR1ABCC2ALDH1A1MCL1 | |
| SCHEMBL20853323 | 0.78 | CA12 (0.39) | ALDH1A1L3MBTL1TSHRKDM4ETP53 | |
| SCHEMBL31487010 | 0.77 | CNR2 (0.47) | CNR2CNR1ALDH1A1MCL1CCR2 | |
| SCHEMBL20853006 | 0.75 | CCR2 (0.54) | ALDH1A1CCR2L3MBTL1KDM4E | |
| SCHEMBL20853229 | 0.74 | KDM4E (0.40) | ALDH1A1L3MBTL1TSHRKDM4ETP53 | |
| SCHEMBL20853261 | 0.74 | TSHR (0.37) | ABCC2ALDH1A1CCR2L3MBTL1GRIN2D | |
| SCHEMBL8562543 | 0.74 | HDAC1 (0.39) | CNR2CNR1ABCC2TSHR | |
| SCHEMBL8562540 | 0.74 | HDAC1 (0.39) | CNR2CNR1ABCC2TSHR | |
| SCHEMBL18247480 | 0.73 | ALDH1A1 (0.42) | CNR2ALDH1A1MCL1CCR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051551-C | Novel pyrrolocarbazoles | HOFFMANN LA ROCHE (CH) | 2000-04-19 | — | — | CN | disclosed |
| CN-1123280-A | Novel pyrrolocarbazoles | HOFFMANN LA ROCHE (CH) | 1996-05-29 | — | — | CN | disclosed |