Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287562 | 0.81 | MAOA (0.47) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL29398266 | 0.75 | MAOA (1.00) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| SCHEMBL4696277 | 0.75 | MAOA (0.90) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL2354794 | 0.75 | MAOA (1.00) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL29358061 | 0.75 | MAOA (1.00) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL41161 | 0.75 | MAOA (1.00) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL18556112 | 0.73 | MAOA (0.95) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL5376736 | 0.73 | MAOA (0.95) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL4560050 | 0.73 | MAOA (0.95) | MAOAKDM4EALDH1A1CYP3A4GLA | |
| Xanthone SCHEMBL11399893 | 0.73 | MAOA (0.95) | MAOAKDM4EALDH1A1CYP3A4GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065786-A1 | SYNTHESIS OF ROCAGLAMIDE NATURAL PRODUCTS VIA PHOTOCHEMICAL GENERATION OF OXIDOPYRYLIUM SPECIES | TRUSTEES OF BOSTON UNIVERSITY | 2011-03-17 | — | — | US | disclosed |
| US-7816544-B2 | Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species | TRUSTEES OF BOSTON UNIVERSITY (US) | 2010-10-19 | — | — | US | disclosed |
| US-20080177093-A1 | Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species | TRUSTEES OF BOSTON UNIVERSITY | 2008-07-24 | — | — | US | disclosed |
| WO-2005092876-A1 | SYNTHESIS OF ROCAGLAMIDE NATURAL PRODUCTS VIA PHOTOCHEMICAL GENERATION OF OXIDOPYRYLIUM SPECIES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065786-A1 | SYNTHESIS OF ROCAGLAMIDE NATURAL PRODUCTS VIA PHOTOCHEMICAL GENERATION OF OXIDOPYRYLIUM SPECIES | NFKBIA, NFE2L2, NFKB1 | MAOA 1402/4885KDM4E 2938/4885ALDH1A1 408/4885 |
| US-20080177093-A1 | Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species | NFKBIA, NFE2L2, NFKB1 | MAOA 1402/4885KDM4E 2938/4885ALDH1A1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.