Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426084 | 0.82 | GCK (0.43) | LMNAGAAKMT2ATSHRALDH1A1 | |
| SCHEMBL27255595 | 0.79 | HTT (0.47) | LMNATSHRALDH1A1SMN1; SMN2TTR | |
| SCHEMBL9577154 | 0.78 | GCK (0.40) | LMNAGAAKMT2ATSHRALDH1A1 | |
| SCHEMBL24631752 | 0.78 | LTA4H (0.53) | LMNAKMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL30134722 | 0.78 | LTA4H (0.53) | LMNAKMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1178876 | 0.76 | LTA4H (0.58) | KMT2AALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL3875262 | 0.76 | LMNA (0.46) | LMNAGAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL10675369 | 0.76 | KMT2A (0.46) | LMNAGAAKMT2ATSHRALDH1A1 | |
| SCHEMBL4963354 | 0.76 | TRIM24 (0.38) | LMNAKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2084338 | 0.76 | NFE2L2 (0.55) | RAB9ATLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613613-B1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| US-7863293-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2011-01-04 | — | — | US | disclosed |
| EP-1613613-A4 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2009-03-25 | — | — | EP | disclosed |
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED CORPORATION (CA) | 2008-10-16 | — | — | US | disclosed |
| US-7291631-B2 | CXCR4 chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2007-11-06 | — | — | US | disclosed |
| EP-1613613-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091518-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2004-10-28 | — | — | WO | disclosed |
| US-20040209921-A1 | CXCR4 chemokine receptor binding comounds | ANORMED CORPORATION (CA) | 2004-10-21 | — | — | US | disclosed |
| US-4491585-A | Combating pests with novel phenoxypyridylmethyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-01 | — | — | US | disclosed |
| EP-0061114-B1 | PHENOXYPYRIDYLMETHYL ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PESTICIDAL COMPOSITIONS | BAYER AG (DE) | 1984-12-12 | — | — | EP | disclosed |
| EP-0076961-A1 | Substituted vinylcyclopropanecarboxylic acid (6-phenoxy-2-pyridinyl)methyl esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1983-04-20 | — | — | EP | disclosed |
| EP-0061114-A1 | Phenoxypyridylmethyl esters, process for their preparation and their use in pesticidal compositions | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209921-A1 | CXCR4 chemokine receptor binding comounds | CXCR4, CXCR1, CXCR3 | LMNA 4525/4885GAA 4838/4885KMT2A 4082/4885 |
| US-20080255197-A1 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | CXCR4, CXCR1, CXCR3 | LMNA 4691/4885GAA 4741/4885KMT2A 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.