Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | IGF2R | P11717 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2085693 | 0.78 | LMNA (0.55) | GCKTSHRKMT2AGAALMNA | |
| SCHEMBL9426084 | 0.78 | GCK (0.43) | GCKTSHRKMT2AGAALMNA | |
| SCHEMBL6054468 | 0.75 | ALDH1A1 (0.44) | GCKTSHREGFRIGF1RIGF2R | |
| SCHEMBL10972250 | 0.74 | LMNA (0.58) | TSHRKMT2AGAALMNAALDH1A1 | |
| SCHEMBL11546337 | 0.70 | GCK (0.62) | GCKKMT2AGAAALDH1A1MEN1 | |
| SCHEMBL4938450 | 0.70 | TDP1 (0.51) | GCKTSHRKMT2AGAALMNA | |
| SCHEMBL6825143 | 0.69 | TSHR (0.41) | GCKTSHREGFRIGF1RIGF2R | |
| SCHEMBL8830149 | 0.68 | LTA4H (0.42) | GCKTSHRKMT2AGAALMNA | |
| SCHEMBL2084341 | 0.68 | ADORA2A (0.51) | GCKTSHRALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2870368 | 0.68 | LTA4H (0.43) | GCKTSHRKMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245073-A | Pesticides, insecticides, hydrogenation | ROUSSEL UCLAF (FR) | 1993-09-14 | — | — | US | disclosed |
| US-5082832-A | Pesticides | ROUSSEL UCLAF (FR) | 1992-01-21 | — | — | US | disclosed |
| US-4925874-A | INSECTICIDES | ROUSSEL UCLAF (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4788305-A | HETEROCYCLIC HEMIACETALS | ROUSSEL UCLAF (FR) | 1988-11-29 | — | — | US | disclosed |