Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RNF4 | P78317 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23257053 | 0.84 | HDAC6 (0.52) | RAB9AALDH1A1LTB4R2HDAC6HDAC2 | |
| SCHEMBL5452605 | 0.83 | NPC1 (1.00) | RAB9AALDH1A1NPC1HTTPAX8 | |
| SCHEMBL14025085 | 0.79 | HDAC6 (0.68) | RAB9AALDH1A1HDAC6HDAC2HDAC8 | |
| SCHEMBL22218111 | 0.78 | HDAC6 (0.62) | RAB9ALTB4R2HDAC6HDAC2HDAC8 | |
| SCHEMBL23257047 | 0.78 | ESRRG (0.61) | RAB9AALDH1A1NPC1HTTPAX8 | |
| SCHEMBL11900090 | 0.77 | HDAC6 (0.85) | RAB9AHDAC6HDAC2HDAC8HDAC1 | |
| SCHEMBL23257050 | 0.74 | ESRRG (0.55) | RAB9ANPC1SMN1; SMN2HDAC6HDAC2 | |
| SCHEMBL7342035 | 0.74 | NPC1 (0.79) | RAB9AALDH1A1NPC1HTTPAX8 | |
| SCHEMBL457082 | 0.73 | HDAC6 (0.79) | RAB9AALDH1A1HDAC6HDAC2HDAC8 | |
| SCHEMBL5226231 | 0.73 | HDAC6 (0.72) | RAB9AALDH1A1NPC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
| EP-3688472-A1 | CONJUGATED PROTEINS AND USES THEREOF | The Scripps Research Institute (US) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019067741-A1 | CONJUGATED PROTEINS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | KEAP1, GSTK1, GSTM2 | RAB9A 2876/4885ALDH1A1 1225/4885NPC1 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.