SCHEMBL20857787

SCHEMBL20857787

c1ccc2c(c1)-c1ccccc1C21c2cc3c4cccc5c6ccccc6n(c3cc2-c2cc3c(cc21)c1cccc2c6ccccc6n3c21)c54

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
DUSP3 P51452 1/20 0.35
LMNA P02545 1/20 0.33
OPRK1 P41145 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.32
FTO Q9C0B1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21717898 0.89 KDM4E (0.36) KDM4EMEN1MAPTKMT2ADUSP3
SCHEMBL20857785 0.89 KDM4E (0.32) KDM4EMEN1MAPTKMT2ALMNA
SCHEMBL21169708 0.86
SCHEMBL21126748 0.86 MEN1 (0.41) KDM4EMEN1MAPTKMT2APOLB
SCHEMBL17050054 0.85 KMT2A (0.36) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL17050075 0.85 KMT2A (0.36) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL17049978 0.85 KMT2A (0.36) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL21453762 0.83 PDK2 (0.33) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL21453760 0.83 KDM4E (0.33) KDM4EMEN1MAPTKMT2AALDH1A1
SCHEMBL20857780 0.82 MAPT (0.37) KDM4EMEN1MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-11569449-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2023-01-31 US disclosed
US-20210336149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-28 US disclosed
WO-2021065772-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC APPLIANCE 出光興産株式会社 2021-04-08 WO disclosed
EP-3723149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND NOVEL COMPOUND Idemitsu Kosan Co., Ltd (JP) 2020-10-14 EP disclosed
US-10680181-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-09 US disclosed
US-10672989-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-02 US disclosed
US-10658594-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-05-19 US disclosed
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-11-21 US disclosed
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed
US-10249832-B1 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L KDM4E 3303/4885MEN1 1048/4885MAPT 1947/4885
US-10249832-B1 Organic electroluminescence device and novel compound OR10J3, KCNH3, OR51E2 KDM4E 2905/4885MEN1 918/4885MAPT 3585/4885
US-10658594-B2 Organic electroluminescence device and novel compound OR10J3, OR51E2, TRPC6 KDM4E 2508/4885MEN1 1026/4885MAPT 3182/4885
US-10680181-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L KDM4E 3303/4885MEN1 1048/4885MAPT 1947/4885
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND OR10J3, OR51E2, TRPC6 KDM4E 2508/4885MEN1 1026/4885MAPT 3182/4885
US-10672989-B2 Organic electroluminescence device and novel compound LEF1, OR10J3, LUC7L2 KDM4E 3077/4885MEN1 1399/4885MAPT 2613/4885
US-20190355914-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L KDM4E 3303/4885MEN1 1048/4885MAPT 1947/4885
US-11569449-B2 Organic electroluminescence device and novel compound PIEZO1, TMEM109, OXA1L KDM4E 3303/4885MEN1 1048/4885MAPT 1947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.