Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.73 |
| ▸ | APP | P05067 | 2/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | TYR | P14679 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | SNCA | P37840 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13934474 | 1.00 | TTR (0.73) | TTRAPPPTPN1EPHX2CA12 | |
| SCHEMBL31560386 | 0.87 | TTR (0.63) | TTRAPPPTPN1EPHX2CA12 | |
| SCHEMBL6960203 | 0.87 | TTR (0.63) | TTRAPPPTPN1EPHX2CA12 | |
| SCHEMBL6960198 | 0.87 | TTR (0.63) | TTRAPPPTPN1EPHX2CA12 | |
| Methylcaffeate SCHEMBL30963730 | 0.85 | APP (1.00) | TTRAPPPTPN1EPHX2CA12 | |
| Methylcaffeate SCHEMBL30637688 | 0.85 | APP (1.00) | TTRAPPPTPN1EPHX2CA12 | |
| Methylcaffeate SCHEMBL198252 | 0.85 | APP (1.00) | TTRAPPPTPN1EPHX2CA12 | |
| Methylcaffeate SCHEMBL817520 | 0.85 | APP (1.00) | TTRAPPPTPN1EPHX2CA12 | |
| SCHEMBL14926722 | 0.84 | TTR (0.59) | TTRAPPPTPN1EPHX2CA12 | |
| SCHEMBL3886157 | 0.83 | TTR (0.76) | TTRAPPCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863332-B2 | Biaromatic compound activators of PPARγ receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-04 | — | — | US | disclosed |
| US-7495111-B2 | Compounds useful as serotonin inhibitors and 5-HT1A agonists and antagonists | WYETH (US) | 2009-02-24 | — | — | US | disclosed |
| CN-101243091-A | Tricyclic compounds useful as 5-serotonin inhibitors and 5-HT1A agonists and antagonists | WYETH CORP (US) | 2008-08-13 | — | — | CN | disclosed |
| US-20070213336-A1 | Biaromatic compound activators of ppargamma receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-09-13 | — | — | US | disclosed |
| CN-101022810-A | Novel biaromatic compounds which activate peroxisome proliferator activated receptor-like receptors and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-08-22 | — | — | CN | disclosed |
| US-20070149585-A1 | Compounds useful as serotonin inhibitors and 5-HT1A agonists and antagonists | WYETH (US) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213336-A1 | Biaromatic compound activators of ppargamma receptors and cosmetic/pharmaceutical compositions comprised thereof | PPARG, PPARA, PPARD | TTR 3344/4885APP 4100/4885PTPN1 1201/4885 |
| US-20070149585-A1 | Compounds useful as serotonin inhibitors and 5-HT1A agonists and antagonists | HTR1A, HTR7, HTR3A | TTR 830/4885APP 2460/4885PTPN1 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.