SCHEMBL20857915

SCHEMBL20857915

c1ccc2c(c1)c1cccc3c4cc5c(ccc6cc7c(cc65)c5cccc6c8ccccc8n7c65)cc4n2c13

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
KMT2A Q03164 4/20 0.41
HPGD P15428 3/20 0.41
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 3/20 0.41
HTT P42858 2/20 0.41
POLB P06746 1/20 0.41
HSD17B10 Q99714 4/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
CYP1A2 P05177 3/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
FTO Q9C0B1 1/20 0.38
CDC25B P30305 1/20 0.35
GPR3 P46089 1/20 0.34
CYP2C19 P33261 1/20 0.33
PTPN1 P18031 1/20 0.33
GAA P10253 2/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20857913 0.93 HSD17B10 (0.43) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL20857811 0.89 KDM4E (0.44) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL23995601 0.88 KDM4E (0.46) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL19564398 0.87 KDM4E (0.42) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL21870158 0.86 KDM4E (0.45) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL20857804 0.86 KDM4E (0.47) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL21870159 0.86 KDM4E (0.47) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL24735191 0.85 KDM4E (0.41) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL20068643 0.85 KMT2A (0.37) ALDH1A1MAPTKMT2AHPGDKDM4E
SCHEMBL20857980 0.85 KDM4E (0.44) ALDH1A1MAPTKMT2AHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-27 US disclosed
US-20210336149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-28 US disclosed
EP-3723149-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND NOVEL COMPOUND Idemitsu Kosan Co., Ltd (JP) 2020-10-14 EP disclosed
US-10672989-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-06-02 US disclosed
US-10658594-B2 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2020-05-19 US disclosed
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed
US-10249832-B1 Organic electroluminescence device and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2019-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128708-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND PIEZO1, TMEM109, OXA1L ALDH1A1 17/4885MAPT 1947/4885KMT2A 3104/4885
US-10249832-B1 Organic electroluminescence device and novel compound OR10J3, KCNH3, OR51E2 ALDH1A1 1491/4885MAPT 3585/4885KMT2A 2567/4885
US-10658594-B2 Organic electroluminescence device and novel compound OR10J3, OR51E2, TRPC6 ALDH1A1 555/4885MAPT 3182/4885KMT2A 2714/4885
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ALDH1A1 160/4885MAPT 966/4885KMT2A 3394/4885
US-20190194215-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND NOVEL COMPOUND OR10J3, OR51E2, TRPC6 ALDH1A1 555/4885MAPT 3182/4885KMT2A 2714/4885
US-10672989-B2 Organic electroluminescence device and novel compound LEF1, OR10J3, LUC7L2 ALDH1A1 272/4885MAPT 2613/4885KMT2A 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.