SCHEMBL20868190

CC(C)C[C@H](CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)CN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C)CC(C)C

nearest known ligand 0.60

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	17/20	0.60

▸	ERAP2	Q6P179	1/20	0.48

▸	ERAP1	Q9NZ08	1/20	0.48

▸	LNPEP	Q9UIQ6	1/20	0.48

▸	HRH1	P35367	1/20	0.47

▸	SLC15A2	Q16348	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18854266	0.94	REN (0.63)	RENHRH1SLC15A2
SCHEMBL18862332	0.87	REN (0.69)	RENERAP2ERAP1LNPEPHRH1
SCHEMBL18857369	0.82	REN (0.57)	RENHRH1SLC15A2
SCHEMBL18862362	0.81	REN (0.63)	RENHRH1
SCHEMBL28042757	0.78	SLC15A2 (0.70)	RENSLC15A2
SCHEMBL18854323	0.78	GHSR (0.59)	REN
SCHEMBL18862365	0.78	REN (0.67)	RENERAP2ERAP1LNPEPHRH1
SCHEMBL22722179	0.78	REN (0.65)	RENERAP2ERAP1LNPEPHRH1
SCHEMBL18862235	0.78	REN (0.65)	RENERAP2ERAP1LNPEPHRH1
SCHEMBL18854269	0.77	GHSR (0.60)	REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019063843-A1	COMPOSITIONS AND METHODS FOR THE DELIVERY OF mRNA TO HEPATIC CELLS	NLIFE THERAPEUTICS, S.L. (ES)	2019-04-04	—	—	WO	disclosed