Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24107257 | 0.80 | NOS3 (0.38) | KDM4EPOLBRAB9AALDH1A1 | |
| SCHEMBL24506836 | 0.80 | KDM4E (0.33) | KDM4EPOLBRAB9A | |
| SCHEMBL16181783 | 0.78 | HSD17B10 (0.33) | KDM4EPOLBRAB9ADHFRALDH1A1 | |
| SCHEMBL25111658 | 0.77 | PIK3CD (0.38) | KDM4EPOLBRAB9ADHFRALDH1A1 | |
| SCHEMBL16302764 | 0.76 | SMN1; SMN2 (0.43) | KDM4EPOLBALDH1A1CYP1A2MAPT | |
| SCHEMBL13253377 | 0.76 | HSP90AA1 (0.36) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL22949453 | 0.74 | L3MBTL1 (0.33) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL22428717 | 0.74 | KDM4E (0.31) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL25623946 | 0.74 | HTT (0.35) | KDM4EALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL17363216 | 0.71 | KDM4E (0.39) | KDM4EPOLBRAB9ADHFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190099747-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | UNIV CALIFORNIA (US) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099747-A1 | NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER | SOD1, MPO, TFRC | KDM4E 3941/4885POLB 195/4885RAB9A 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.