Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.68 |
| ▸ | MAOA | P21397 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715160 | 0.93 | MAOA (0.75) | CISD1MAOAALDH1A1MAOBNPSR1 | |
| SCHEMBL10487963 | 0.93 | MAOA (0.75) | CISD1MAOAALDH1A1MAOBNPSR1 | |
| SCHEMBL15761669 | 0.86 | MAOA (0.56) | CISD1MAOAALDH1A1MAOBKMT2A | |
| SCHEMBL14560445 | 0.86 | MAOA (0.65) | CISD1MAOAALDH1A1MAOBKMT2A | |
| SCHEMBL24129903 | 0.86 | CISD1 (0.67) | CISD1MAOAALDH1A1MAOBNPSR1 | |
| SCHEMBL2447131 | 0.86 | CISD1 (0.67) | CISD1MAOAALDH1A1MAOBNPSR1 | |
| SCHEMBL2447134 | 0.86 | CISD1 (0.67) | CISD1MAOAALDH1A1MAOBNPSR1 | |
| SCHEMBL13726431 | 0.85 | MEN1 (0.67) | MAOAALDH1A1MAOBKMT2AMAPT | |
| SCHEMBL1655605 | 0.85 | SENP8 (0.63) | MAOAALDH1A1MAOBKMT2AMAPT | |
| SCHEMBL13726429 | 0.85 | MEN1 (0.67) | MAOAALDH1A1MAOBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190099453-A1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2019-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099453-A1 | MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE | PYGL, HNF4A, ATF1 | CISD1 3219/4885MAOA 2252/4885ALDH1A1 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.