Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061268 | 0.90 | METAP2 (0.33) | TRPA1AKT1STAT3GAABACE1 | |
| SCHEMBL22061292 | 0.90 | METAP2 (0.33) | TRPA1AKT1STAT3GAABACE1 | |
| SCHEMBL20006392 | 0.81 | TRPA1 (0.36) | HTR1ATRPA1AKT1BACE1METAP2 | |
| SCHEMBL20870189 | 0.80 | PDK2 (0.33) | TRPA1AKT1GAAMETAP2 | |
| SCHEMBL20870405 | 0.79 | KCNH2 (0.36) | TRPA1AKT1 | |
| SCHEMBL22279702 | 0.79 | SKP2 (0.36) | TAS1R3TAS1R1HTR1ATRPA1AKT1 | |
| SCHEMBL9449596 | 0.75 | TRPA1 (0.40) | TRPA1AKT1GAABACE1METAP2 | |
| SCHEMBL21228550 | 0.73 | LMNA (0.39) | GAAMETAP2 | |
| SCHEMBL20870143 | 0.73 | AR (0.36) | TRPA1AKT1BACE1METAP2 | |
| SCHEMBL22279892 | 0.71 | HTR1A (0.42) | HTR1ATRPA1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063015-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS RORγ INHIBITOR | 正大天晴药业集团股份有限公司 | 2019-04-04 | — | — | WO | disclosed |