Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449596 | 0.86 | TRPA1 (0.40) | TRPA1CYP1A2CYP2A6AKT1PLK1 | |
| SCHEMBL20870495 | 0.81 | TAS1R3 (0.34) | TRPA1AKT1BACE1HTR1AMETAP2 | |
| SCHEMBL20870143 | 0.80 | AR (0.36) | TRPA1CYP1A2CYP2A6AKT1PLK1 | |
| SCHEMBL22061268 | 0.79 | METAP2 (0.33) | TRPA1AKT1PLK1BACE1MTNR1A | |
| SCHEMBL22061292 | 0.79 | METAP2 (0.33) | TRPA1AKT1PLK1BACE1MTNR1A | |
| SCHEMBL21377563 | 0.78 | AOC1 (0.40) | PLK1BACE1ALOX5CNR1CNR2 | |
| SCHEMBL25665126 | 0.77 | TRPA1 (0.43) | TRPA1CYP1A2CYP2A6PLK1TAAR1 | |
| SCHEMBL20615440 | 0.77 | CHRNB2 (0.41) | CYP1A2TAAR1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL20708199 | 0.77 | GAA (0.43) | TAAR1SLC6A4NPC1ALDH1A1LMNA | |
| SCHEMBL11791277 | 0.75 | TRPA1 (0.41) | TRPA1CYP1A2CYP2A6AKT1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299373-A2 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | PhytoHealth Corporation (TW) | 2018-03-28 | — | — | EP | disclosed |