Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12281605 | 0.80 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL6981521 | 0.73 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL4031020 | 0.73 | TAS2R14 (0.36) | — | |
| SCHEMBL16373264 | 0.71 | GLA (0.32) | HSD11B1 | |
| SCHEMBL4030375 | 0.70 | GLA (0.30) | — | |
| SCHEMBL20876173 | 0.69 | HTT (0.47) | — | |
| SCHEMBL28007356 | 0.68 | MGLL (0.31) | — | |
| SCHEMBL16661404 | 0.68 | P2RX7 (0.32) | — | |
| SCHEMBL12806719 | 0.68 | AR (0.33) | — | |
| SCHEMBL18149729 | 0.67 | GRIA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384074-B2 | Pesticidally active pyrrole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-07-12 | — | — | US | disclosed |
| US-11384074-B2 | Pesticidally active pyrrole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-07-12 | — | — | US | disclosed |
| US-20200399257-A1 | Pesticidally Active Pyrrole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-24 | — | — | US | disclosed |
| US-20200399257-A1 | Pesticidally Active Pyrrole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-24 | — | — | US | disclosed |
| EP-3692038-A1 | PESTICIDALLY ACTIVE PYRROLE DERIVATIVES | Syngenta Participations AG (CH) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019068820-A1 | PESTICIDALLY ACTIVE PYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
| WO-2019068820-A1 | PESTICIDALLY ACTIVE PYRROLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384074-B2 | Pesticidally active pyrrole derivatives | ACHE, DDT, CAT | HSD11B1 4022/4885 |
| US-20200399257-A1 | Pesticidally Active Pyrrole Derivatives | ACHE, DDT, CAT | HSD11B1 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.