Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14691212 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL8378174 | 0.80 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20879183 | 0.80 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20879157 | 0.79 | SMN1; SMN2 (0.36) | MAPTALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL13603840 | 0.78 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL20879248 | 0.77 | MEP1B (0.34) | MAPTALDH1A1KDM4EGAARAB9A | |
| SCHEMBL20879161 | 0.77 | ALDH1A1 (0.39) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8376101 | 0.74 | KMT2A (0.40) | MAPTALDH1A1MEN1KMT2AF2 | |
| SCHEMBL29173926 | 0.74 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11159138 | 0.71 | L3MBTL1 (0.47) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070087-B1 | INTERMEDIATES FOR THE SYNTHESIS OF CYCLIC P1 LINKERS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-04-10 | — | — | EP | disclosed |