Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 6/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8378174 | 0.81 | MAPT (0.48) | KMT2AMEN1ALDH1A1MAPTF2 | |
| SCHEMBL5891521 | 0.78 | ALDH1A1 (0.55) | KMT2AALDH1A1MAPTNPC1GAA | |
| SCHEMBL13603840 | 0.76 | MAPT (0.44) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL8392473 | 0.76 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL20879153 | 0.74 | MAPT (0.40) | KMT2AMEN1ALDH1A1MAPTF2 | |
| SCHEMBL14691212 | 0.74 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1MAPTF2 | |
| SCHEMBL29173926 | 0.72 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL8421898 | 0.72 | BCL2A1 (0.44) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL734811 | 0.71 | RAB9A (0.42) | MAPTSMN1; SMN2POLB | |
| SCHEMBL11159138 | 0.70 | L3MBTL1 (0.47) | KMT2AMEN1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885995-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-03-23 | — | — | US | disclosed |