SCHEMBL208907

SCHEMBL208907

COc1cc(OC)c(NC(=O)c2ccc(Cc3cc4c(cc3C)C(C)(C)CCC4(C)C)o2)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 1.00
FPR1 P21462 1/20 1.00
GPR183 P32249 1/20 1.00
GPR119 Q8TDV5 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31060713 1.00 GNRHR (1.00) GNRHRFPR1GPR183GPR119
SCHEMBL5834658 0.90 GNRHR (0.82) GNRHRFPR1GPR183GPR119
SCHEMBL5835109 0.89 GNRHR (0.81) GNRHRFPR1GPR183GPR119
SCHEMBL6224065 0.85 GNRHR (0.75) GNRHRFPR1GPR183GPR119
SCHEMBL17549863 0.83 GNRHR (0.71) GNRHRFPR1GPR183GPR119
SCHEMBL17549867 0.83 GNRHR (0.71) GNRHRFPR1GPR183GPR119
SCHEMBL5266205 0.83 GNRHR (0.71) GNRHRFPR1GPR183GPR119
SCHEMBL5705276 0.83 GNRHR (0.71) GNRHRFPR1GPR183GPR119
SCHEMBL17552170 0.82 GNRHR (0.70) GNRHRFPR1GPR183GPR119
SCHEMBL16238424 0.82 GNRHR (0.70) GNRHRFPR1GPR183GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693484-B Simple synthesis method of 1-bromodibenzofuran 武汉理工大学 2024-11-12 CN claimed
CN-115947704-B Preparation method of organic luminescent material intermediate 1-bromodibenzofuran 武汉理工大学深圳研究院 2024-04-09 CN claimed
CN-115677637-B Simple preparation method of 1-bromodibenzofuran 安徽秀朗新材料科技有限公司 2024-02-23 CN claimed
CN-116693484-A Simple synthesis method of 1-bromodibenzofuran 武汉理工大学 2023-09-05 CN claimed
CN-115947704-A Preparation method of organic luminescent material intermediate 1-bromodibenzofuran 武汉理工大学深圳研究院 2023-04-11 CN claimed
CN-115677637-A Simple preparation method of 1-bromodibenzofuran 萍乡学院 2023-02-03 CN claimed
WO-2022208382-A1 NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME 동화약품주식회사 2022-10-06 WO claimed
CN-114129584-A Application of phillyrin, phillyrin derivatives and composition of phillyrin and forsythiaside in resisting cytomegalovirus 富力 2022-03-04 CN claimed
CN-122005489-A FACOD@DSPE nano particle, preparation method and application thereof in antibiosis/sterilization 广西中医药大学第一附属医院(广西中医医院) 2026-05-12 CN disclosed
US-12551490-B2 Heterocyclic modulators of lipid synthesis SAGIMET BIOSCIENCES INC. (US) 2026-02-17 US disclosed
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE SLINGSHOT BIOSCIENCES, INC. (US) 2025-12-25 US disclosed
WO-2025233259-A1 COMPOUND FOR USE IN THE TREATMENT OF DEPRESSION, OBSESSIVE-COMPULSIVE DISORDER, POST-TRAUMATIC STRESS DISORDER AND/OR BORDERLINE PERSONALITY DISORDER BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-11-13 WO disclosed
EP-3789389-B1 CRYSTALLINE FORM OF (S)-N-[5-[1-(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYLSULFONYL)ETHYL]-4,6-DIOXO-5,6-DIHYDRO-4H-THIENO[3,4-C]PYRROLE-1-YL]ACETAMIDE TIANJIN HEMAY PHARMACEUTICAL CO LTD (CN) 2025-10-08 EP disclosed
EP-4611741-A1 TARGETING ALLOSTERIC AND ORTHOSTERIC POCKETS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE Petra Pharma Corporation (US) 2025-09-10 EP disclosed
US-20050250793-A1 Preventives/remedies for hot flash TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-11-10 US disclosed
US-20050214330-A1 Process for producing sustained-release composition TAKEDA PHARMACEUTICAL COMPANY LIMITED 2005-09-29 US disclosed
EP-1532985-A1 PROCESS FOR PRODUCING SUSTAINED-RELEASE COMPOSITION Takeda Pharmaceutical Company Limited (JP) 2005-05-25 EP disclosed
EP-1495768-A1 PREVENTIVES/REMEDIES FOR HOTFLASH Takeda Pharmaceutical Company Limited (JP) 2005-01-12 EP disclosed
US-20040235748-A1 AGENTS FOR PREVENTING POSTOPERATIVE RECURRENCE OF PREMENOPAUSAL BREAST CANCER TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-11-25 US disclosed
EP-1382350-A1 PREVENTIVES FOR POSTOPERATIVE RECURRENCE OF PREMENOPAUSAL BREAST CANCER Takeda Chemical Industries, Ltd. (JP) 2004-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040235748-A1 AGENTS FOR PREVENTING POSTOPERATIVE RECURRENCE OF PREMENOPAUSAL BREAST CANCER GNRHR, BRCA1, SHBG GNRHR 1/4885FPR1 1137/4885GPR183 165/4885
US-20050250793-A1 Preventives/remedies for hot flash GNRHR, SHBG, FSHR GNRHR 1/4885FPR1 774/4885GPR183 317/4885
US-12551490-B2 Heterocyclic modulators of lipid synthesis FASN, FADS1, FADS2 GNRHR 3928/4885FPR1 245/4885GPR183 1309/4885
US-20050214330-A1 Process for producing sustained-release composition FIBP, PGF, GHRHR GNRHR 94/4885FPR1 1302/4885GPR183 1533/4885
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE CD4, ICOS, CD69 GNRHR 1250/4885FPR1 990/4885GPR183 2723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.