SCHEMBL2089271

SCHEMBL2089271

Cc1ccc(OCO)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.52
DRD2 P14416 1/20 0.48
DRD4 P21917 1/20 0.48
DRD3 P35462 1/20 0.48
ACHE P22303 1/20 0.48
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 2/20 0.46
MAOB P27338 1/20 0.46
GAA P10253 1/20 0.46
KCNH2 Q12809 1/20 0.45
NPC1 O15118 1/20 0.44
PARP10 Q53GL7 1/20 0.44
USP2 O75604 1/20 0.44
TSHR P16473 1/20 0.44
NQO1 P15559 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15250532 0.93 HPGD (0.49) WDR5L3MBTL1DRD2DRD4DRD3
SCHEMBL22941843 0.87 MAPT (0.45) WDR5L3MBTL1DRD2DRD4DRD3
SCHEMBL21791988 0.87 PPARA (0.47) WDR5L3MBTL1DRD2DRD4DRD3
SCHEMBL717121 0.86 NQO1 (0.47) L3MBTL1LMNAGAAPARP10TSHR
SCHEMBL15250528 0.84 USP2 (0.43) WDR5L3MBTL1DRD2DRD4DRD3
SCHEMBL15250545 0.84 USP2 (0.43) WDR5L3MBTL1DRD2DRD4DRD3
SCHEMBL15250530 0.82 PPARA (0.44) WDR5L3MBTL1DRD2DRD4DRD3
SCHEMBL15250539 0.82 RELA (0.53) WDR5MAPTHPGDMAOBNPC1
SCHEMBL15250549 0.82 RELA (0.53) WDR5MAPTHPGDMAOBNPC1
SCHEMBL15250546 0.82 PPARA (0.44) WDR5L3MBTL1DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133211-A1 PHOTOCHROMIC CYCLIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC CYCLIC COMPOUND TOKUYAMA CORPORATION (JP) 2023-05-04 US disclosed
CN-108567129-B N-acyl-amino acid derivatives for improving flavor profile of edible compositions 奇华顿股份有限公司 2021-10-29 CN disclosed
CN-105658086-B Method for purifying N-acyl amino acids by using propylene glycol as extraction solvent 奇华顿股份有限公司 2021-04-06 CN disclosed
CN-106659204-B Sweetener composition 奇华顿股份有限公司 2021-03-02 CN disclosed
US-20210010026-A1 RETROVIRAL TRANSDUCTION USING POLOXAMERS AFFINI-T THERAPEUTICS, INC. 2021-01-14 US disclosed
CN-112074195-A Apple vinegar nutritional supplement 高丽营养有限公司 2020-12-11 CN disclosed
WO-2016201354-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER GLOBAVIR BIOSCIENCES, INC. (US) 2016-12-15 WO disclosed
EP-2695878-B1 Multi-functional monomer having a photocreative group, alignment film for LCD using the monomer, and LCD comprising the alignment film LG CHEMICAL LTD (KR) 2015-06-10 EP disclosed
US-8163753-B2 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-04-24 US disclosed
US-7892711-B2 Azo compound, composition for photo-alignment film using the same, and method for producing photo-alignment film DIC CORPORATION (JP) 2011-02-22 US disclosed
US-7678445-B2 Extruded toner receiver layer for electrophotography EASTMAN KODAK COMPANY (US) 2010-03-16 US disclosed
US-20090088545-A1 Polymerziable liquid crystal compound, polymerziable liquid crystal composition comprising the same, and polymer produced using them NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-04-02 US disclosed
EP-1678185-B1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMA CO LTD (JP) 2008-10-08 EP disclosed
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis OTSUKA PHAMACEUTICAL CO., LTD. (JP) 2008-05-22 US disclosed
US-20070254220-A1 Azo Compound, Composition For Photo-Alignment Film Using The Same, And Method For Producing Photo-Alignment Film DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-11-01 US disclosed
US-20070212527-A1 EXTRUDED TONER RECEIVER LAYER FOR ELECTROPHOTOGRAPHY BANK OF AMERICA, N.A., AS AGENT 2007-09-13 US disclosed
US-7264867-B2 Extruded toner receiver layer for electrophotography EASTMAN KODAK COMPANY (US) 2007-09-04 US disclosed
US-7264664-B2 Ink composition, recording method and recorded image utilizing the same, ink set and ink head SHARP KABUSHIKI KAISHA (JP) 2007-09-04 US disclosed
EP-1678185-A1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-07-12 EP disclosed
WO-2005042542-A1 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis NR2C2, NR0B2, NR4A2 WDR5 1784/4885L3MBTL1 2575/4885DRD2 409/4885
US-20070254220-A1 Azo Compound, Composition For Photo-Alignment Film Using The Same, And Method For Producing Photo-Alignment Film CRY1, MMS19, C1R WDR5 1066/4885L3MBTL1 2938/4885DRD2 2772/4885
US-20210010026-A1 RETROVIRAL TRANSDUCTION USING POLOXAMERS CD44, CD74, POLI WDR5 1491/4885L3MBTL1 3602/4885DRD2 4416/4885
US-20090088545-A1 Polymerziable liquid crystal compound, polymerziable liquid crystal composition comprising the same, and polymer produced using them ZYX, MBD2, CRYZ WDR5 1758/4885L3MBTL1 1101/4885DRD2 457/4885
US-20230133211-A1 PHOTOCHROMIC CYCLIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC CYCLIC COMPOUND CRY1, CCNL2, CCNT1 WDR5 583/4885L3MBTL1 2257/4885DRD2 2984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.