Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20895111 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL4425022 | 0.74 | CYP1A2 (0.36) | — | |
| SCHEMBL18889257 | 0.70 | SLC9A1 (0.41) | PTGS2RPS6KA3 | |
| SCHEMBL18889242 | 0.69 | MAPK14 (0.48) | EIF4ELMNARPS6KA3 | |
| SCHEMBL20895237 | 0.68 | RIPK1 (0.40) | SMN1; SMN2ALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL20895135 | 0.67 | CYP17A1 (0.39) | PTGS2RPS6KA3 | |
| SCHEMBL693996 | 0.65 | PTGS2 (0.36) | PTGS2 | |
| SCHEMBL20895093 | 0.65 | GSK3A (0.48) | SMN1; SMN2RPS6KA3 | |
| SCHEMBL1262207 | 0.63 | GRM2 (0.48) | PTGS2SMN1; SMN2KDM4ENPC1TP53 | |
| SCHEMBL31067069 | 0.63 | GRM2 (0.48) | PTGS2SMN1; SMN2KDM4ENPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176163-B1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | IAC IN NAT UNIV CHUNGNAM (KR) | 2019-04-17 | — | — | EP | claimed |