Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 3/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.45 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321698 | 0.72 | PLOD2 (0.49) | PLOD2PLOD3PLOD1CES1ALDH1A1 | |
| SCHEMBL17951545 | 0.68 | CES1 (0.42) | CES1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL23511768 | 0.66 | — | — | |
| SCHEMBL1279224 | 0.65 | — | — | |
| SCHEMBL6979211 | 0.64 | RAB9A (0.58) | ALDH1A1HPGDTSHRPOLBSMN1; SMN2 | |
| SCHEMBL195358 | 0.63 | ERCC5 (0.59) | PLOD2PLOD3PLOD1CES1ALDH1A1 | |
| SCHEMBL18622294 | 0.63 | PLOD2 (0.55) | PLOD2PLOD3PLOD1CES1KDM4E | |
| SCHEMBL751818 | 0.62 | GSK3B (0.56) | PLOD2PLOD3PLOD1CES1ALDH1A1 | |
| SCHEMBL10631235 | 0.62 | ERCC5 (0.57) | PLOD2PLOD3PLOD1CES1ALDH1A1 | |
| SCHEMBL21408730 | 0.62 | PLOD2 (0.67) | PLOD2PLOD3PLOD1CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10835895-B2 | Compound and synthesis method therefor | THE UNIVERSITY OF TOKYO (JP) | 2020-11-17 | — | — | US | disclosed |
| US-20190111418-A1 | COMPOUND AND SYNTHESIS METHOD THEREFOR | THE UNIVERSITY OF TOKYO (JP) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10835895-B2 | Compound and synthesis method therefor | GOT1, GOT2, SLC39A11 | PLOD2 3759/4885PLOD3 4837/4885PLOD1 3345/4885 |
| US-20190111418-A1 | COMPOUND AND SYNTHESIS METHOD THEREFOR | GOT1, GOT2, SLC39A11 | PLOD2 3851/4885PLOD3 4841/4885PLOD1 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.