Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 10/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.50 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.50 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.48 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232134 | 0.85 | FAAH (0.46) | PRKAA2GPR183FAAHPOLBPKM | |
| SCHEMBL209280 | 0.84 | TBK1 (0.55) | TRPV6MEN1KMT2AATMPRKAA2 | |
| SCHEMBL16152472 | 0.83 | GPR183 (0.51) | TRPV6MEN1KMT2AATMPRKAA2 | |
| SCHEMBL14839769 | 0.82 | MEN1 (0.53) | TRPV6MEN1KMT2AATMPRKAA2 | |
| SCHEMBL18713087 | 0.81 | TRPV6 (0.57) | TRPV6MEN1KMT2AHRH3 | |
| SCHEMBL18713082 | 0.81 | TRPV6 (0.57) | TRPV6PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20413614 | 0.80 | TRPV6 (0.56) | TRPV6MEN1KMT2AATMPRKAA2 | |
| SCHEMBL23589183 | 0.80 | HRH3 (0.67) | TRPV6PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29259746 | 0.80 | TRPV6 (0.56) | TRPV6MEN1KMT2AATMPRKAA2 | |
| SCHEMBL21608370 | 0.79 | TBK1 (0.49) | TRPV6MEN1KMT2AATMPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-1963315-B1 | ENZYME INHIBITORS | CANCER REC TECH LTD (GB) | 2014-10-08 | — | — | EP | disclosed |
| US-8088761-B2 | Enzyme inhibitors | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2012-01-03 | — | — | US | disclosed |
| US-20090247507-A1 | Enzyme Inhibitors | THE INSTITUTE OF CANCER RESEARCH (GB) | 2009-10-01 | — | — | US | disclosed |
| EP-1963315-A2 | ENZYME INHIBITORS | The Institute of Cancer Research (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072017-A2 | ENZYME INHIBITORS | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247507-A1 | Enzyme Inhibitors | AURKC, AURKB, AURKA | TRPV6 4269/4885MEN1 471/4885KMT2A 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.