SCHEMBL20915059

SCHEMBL20915059

CCCC(CC(O)c1ccc(OCc2ccccc2)cc1)NC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.48
ACACB O00763 1/20 0.47
LMNA P02545 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HDAC3 O15379 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46
NCOR2 Q9Y618 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAOB P27338 1/20 0.45
FFAR1 O14842 1/20 0.45
CNR2 P34972 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4435918 0.82 ALOX5 (0.53) ALOX5ACACBLMNAL3MBTL1HDAC3
SCHEMBL19329926 0.80 HDAC3 (0.53) LMNAL3MBTL1HDAC3HDAC1HDAC2
SCHEMBL22362709 0.76 POLB (0.49) ALOX5ACACBLMNAL3MBTL1
SCHEMBL20425136 0.75 LMNA (0.56) ALOX5ACACBLMNAL3MBTL1MAOB
SCHEMBL6190389 0.75 LMNA (0.58) ALOX5LMNAL3MBTL1MAOB
SCHEMBL20425199 0.75 NR4A1 (0.53) ALOX5ACACBLMNAMAOBFFAR1
SCHEMBL22362711 0.75 BCHE (0.53) ALOX5ALDH1A1
SCHEMBL20835322 0.75 BCHE (0.53) ALOX5ALDH1A1
SCHEMBL20835321 0.75 BCHE (0.53) ALOX5ALDH1A1
SCHEMBL232540 0.74 LMNA (0.59) ALOX5LMNAL3MBTL1ALDH1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2019-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA SLC5A2, SLC5A1, SLC2A2 ALOX5 4351/4885ACACB 650/4885LMNA 2416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.