Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197798 | 0.74 | PDGFRB (0.46) | EGFRPDGFRBPDGFRAKDM4E | |
| SCHEMBL660837 | 0.71 | HTR1A (0.43) | EGFRPDGFRBPDGFRAKDM4E | |
| SCHEMBL5658397 | 0.70 | KDM4E (0.43) | LOXLOXL2NNMTGABRPGABRD | |
| SCHEMBL4471481 | 0.68 | ALDH1A1 (0.46) | CYP2A6KDM4E | |
| SCHEMBL9911108 | 0.68 | EGFR (0.42) | LOXLOXL2NNMTGABRPGABRD | |
| SCHEMBL590041 | 0.68 | LMNA (0.43) | EGFRPDGFRBPDGFRAKDM4E | |
| SCHEMBL3936581 | 0.66 | — | — | |
| SCHEMBL25190502 | 0.64 | GABRP (0.38) | LOXLOXL2NNMTGABRPGABRD | |
| SCHEMBL4054735 | 0.64 | PDE10A (0.34) | NNMTPDGFRBPDGFRA | |
| SCHEMBL24393384 | 0.64 | GABRP (0.41) | LOXLOXL2NNMTGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078968-A2 | CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS | ANGEX PHARMACEUTICAL, INC. (US) | 2019-04-25 | — | — | WO | claimed |