Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924189 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL16071797 | 0.81 | HSD17B1 (0.48) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL374670 | 0.81 | HSD17B1 (0.48) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL4293875 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL9837774 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL4768199 | 0.80 | GAA (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7959792 | 0.78 | MAPT (0.50) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL2191052 | 0.77 | HSD17B1 (0.75) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL2502603 | 0.77 | MAPT (0.71) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT | |
| SCHEMBL30622065 | 0.77 | HSD17B1 (0.75) | SMN1; SMN2HSD17B1HSD17B2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473624-B1 | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-05-11 | — | — | EP | disclosed |
| EP-3473624-A1 | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2019-04-24 | — | — | EP | disclosed |